UDP disodium salt

CAS No. 27821-45-0

UDP disodium salt( Uridine 5'-diphosphate disodium salt hyd )

Catalog No. M19585 CAS No. 27821-45-0

UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6) stimulating the production of inflammatory mediators phagocytosis and vasoconstriction. UDP also acts as an antagonist of P2Y14.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 41 In Stock
500MG 87 In Stock
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Biological Information

  • Product Name
    UDP disodium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6) stimulating the production of inflammatory mediators phagocytosis and vasoconstriction. UDP also acts as an antagonist of P2Y14.
  • Description
    UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6) stimulating the production of inflammatory mediators phagocytosis and vasoconstriction. UDP also acts as an antagonist of P2Y14.
  • In Vitro
    RT-PCRCell Line:Primary microglia Concentration:100 μM Incubation Time:For 15 min Result:Significantly induced microglial CCL2 and CCL3 mRNA expression.
  • In Vivo
    ——
  • Synonyms
    Uridine 5'-diphosphate disodium salt hyd
  • Pathway
    Neuroscience
  • Target
    P2 Receptor
  • Recptor
    P2Y6| P2Y14
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    27821-45-0
  • Formula Weight
    466.14
  • Molecular Formula
    C9H14N2Na2O13P2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    [Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)n1ccc(=O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jacobson K.A. et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 5(1) 75-89 (2009).
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